Optimize your clinical trial design

Guide to Sample Size

Sample Size for Complex Endpoints

In this webinar we look at sample size for the proportional odds model for ordinal data, the Win Ratio statistic for composite endpoints and the MaxCombo test for complex survival analysis.

Guide to Sample Size

Why is Sample Size important?

Why is Sample Size important? Determination of the sample size is critical to influencing the power of a statistical test. nQuery is used for sample size and power calculation in successful clinical trials.

Guide to Sample Size

Sample Size for Statistical Intervals

Learn about different statistical intervals & methods to calculate the required sample size for confidence, prediction, tolerance and credible intervals.

Guide to Sample Size

Advanced Sample Size Determination for Counts and Rates

Learn about advanced sample size determination for counts and rates, overcoming challenges like overdispersion and unequal follow-up.

Guide to Sample Size

nQuery is now part of Dotmatics

To our Statsols customers, for more than 20 years Statsols has worked with researchers and biostatisticians around the world to make clinical trials faster, less costly and more successful through our trial design platform nQuery.

Guide to Sample Size

Sample Size & Prediction Calculation Interactions

[Video] Clinical trial milestone prediction for a survival group sequential design & sample size calculations for clinical prediction models.

Guide to Sample Size

Improving Your Pre-Trial Milestone Predictions

In this webinar, we provide an introduction to clinical trial milestone prediction and the options available to make these predictions before and during a clinical trial.

Adaptive Clinical Trials

How to predict trial milestones for survival or time to event endpoints

[GUIDE] Accurately predicting your trial milestones when Survival or Time to event endpoints are being used can be very challenging. Read our guide to learn how.

Guide to Sample Size

Designing Sequential Clinical Trials

Sequential designs - A powerful class of Adaptive trial designs that have become common in the clinical trial landscape. Learn how to design them correctly.

Guide to Sample Size

What statistical test should I use?

What statistical test should I use? The design of a study is more important than the analysis. Use this guide

Guide to Sample Size

Crossover & Cluster Randomized Trials

We explore crossover & cluster randomized trials as alternative study designs and randomization schemes.

Guide to Sample Size

Clinical Trial Design Trends in 2022

[Video] Covid-19 has led to a dramatic change in the scope and expectations for trial design. What does this mean for clinical trialists and biostatisticians in 2022?

Guide to Sample Size

Clinical Trial Design | This year's most popular topics

Explore the latest trends in clinical trial design with a focus on vaccine and Bayesian trial designs, and survival trial milestone predictions.

Guide to Sample Size

Overcoming Challenges in Survival Analysis 

[Video] Explore some common challenges faced when designing clinical trials with survival endpoints, and the solutions for these problems.

Guide to Sample Size

How to predict key events in survival analysis trials

[Video] How to predict key events in survival analysis trials. Using Simulation to project event targets and how to get a study back on track.

Guide to Sample Size

Predicting Key Study Milestones

[Video] Predicting Key Study Milestones. Using Simulation for Enrollment and Event Predictions.

Guide to Sample Size

Sample Size for Oncology Trials

In this webinar, we review common survival analysis models & evaluate their impact of delayed effect models and adaptive design

Guide to Sample Size

Bayesian Approaches to Interval Estimation & Hypothesis testing

[Video] We explore the characteristics of Bayesian sample size and discuss methods for interval estimation and hypothesis testing using the Bayesian framework.

Guide to Sample Size

Design and Sample Size for Vaccine Trials | Case Study of Covid-19

Explore the complexities of vaccine trial design, focusing on COVID-19 trials. Learn about sample size, safety considerations, and design innovations.

Guide to Sample Size

Phase II Oncology Trial Designs

Explore unique issues in phase II oncology trial designs and adaptive solutions. Learn about Simon's, Bryant & Day's, and Lin & Shih's designs.

Guide to Sample Size

Choosing the right sample size method

Explore proportions options, flexible survival analysis, and non-proportional hazards in this insightful webinar.

Guide to Sample Size

2021 Trends In Biostatistics - Latest developments in clinical trial design

[Video] We examine how industry changes are impacting clinical trials and what developments Biostatisticians should be aware of in 2021.

Guide to Sample Size

This year's most popular clinical trial design topics

[Video] nQuery Researcher Brian Fox demonstrates some of this year's most popular webinar topics through practical sample size examples.

Guide to Sample Size

Impact of COVID-19 in clinical trials [webinar]

[Webinar] Guest Presenter Dr. Luis Rojas, former Senior Principal Statistician at Parexel provides his insights and feedback on the impact of Covid-19 in clinical trials, and how to navigate them.

Guide to Sample Size

Flexible Clinical Trial Design | Survival, Stepped-Wedge & MAMS

[Video] As clinical trials increase in complexity we explore the flexibility available to you when designing modern clinical trials.

Guide to Sample Size

Designing MAMS Trials | Advantages, issues and sample size

[Video] MAMS trials can provide a quick and efficient evaluation of multiple treatments, targets or doses under a single study protocol.

Guide to Sample Size

Optimizing Oncology Trial Design  (FAQs & Common Issues)

[Video] We examine how to optimize oncology trial design. We also cover FAQs and common issues that arise.

Guide to Sample Size

MCP-Mod | Optimizing Phase II Dose Selection

[Video] Continuous & non-continuous endpoints - we examine how to optimize phase II dose selection

Guide to Sample Size

Why to include Bayesian statistics when planning your frequentist trial

[Video] Learn about why you should integrate Bayesian statistics when planning a trial and how you can start integrating Bayesian methods into your frequentist work.

Guide to Sample Size

Sample Size For Survival Analysis

[Video] Practical examples of the new and established design strategies that are available to you for planning a survival analysis.

Guide to Sample Size

Adaptive Designs for Phase II Trials

[Webinar] Reduce the cost and time of a Phase II trial by using adaptive designs. Learn via practical examples.

Guide to Sample Size

5 Ways to Optimize Trial Designs

What are the new methods to optimize trial design? We examine 5 ways to optimize and improve your trial design.

Guide to Sample Size

MCP-Mod (Multiple Comparisons Procedure - Modelling) Explained

MCP-Mod or Multiple Comparisons Procedure - Modelling is an increasingly popular statistical methodology that can generate superior statistical evidence from Phase II trials regards dose selection.

News & Events

JSM 2020 - Virtual Event - Everything you need to know

JSM 2020 - Everything you need to know - Joint Statistical Meetings 2020 in Philadelphia. Now online.

Guide to Sample Size

Optimizing Oncology Trial Design [Webinar on Demand]

In this free webinar we examine how to optimize your oncology trial design. Specifically, we will examine the frequently asked questions and common issues that arise.

Guide to Sample Size

Recurrent Event Studies - Model choices, pitfalls and group sequential design

Recurring events are common in clinical trials (e.g. COPD exacerbations, MS relapses) but have often been analysed using survival models or other approximations. But these simple approaches fail to use every event. Here we provide alternatives and solutions to this problem.

Adaptive Clinical Trials

Adaptive Design with Ronan Fitzpatrick & Stephen Senn

Learn from experts Ronan Fitzpatrick & Stephen Senn about Adaptive Design & Early Phase Trials in Clinical Research.

Guide to Sample Size

FDA Guidance on Conduct of Clinical Trials during the COVID-19 Pandemic

The FDA issued guidance on how the Covid-19 Pandemic may affect the conduct of clinical trials. Here is an overview of the FDA Guidance on Conduct of Clinical Trials during the COVID-19 Pandemic.

Guide to Sample Size

Designing studies with recurrent events

Model choices, pitfalls and group sequential design - we examine designing studies with recurrent events.

Guide to Sample Size

Companies with the most drug approvals for 2019

2019 was another very busy year at FDA CDER with 89 approvals across novel drugs, new & expanded uses, biosimilars, new formulations and new dosage forms. We examine the companies with the most approvals for 2019.

Guide to Sample Size

2020 Trends In Biostatistics [Webinar]

In this free webinar we will examine how industry changes are impacting clinical trials and what developments Biostatisticians should be aware of in 2020.

Guide to Sample Size

5 Reasons to upgrade to nQuery v8.5 [Video]

"5 reasons to upgrade to nQuery v8.5" answers all the questions you may have about moving to the newest version of nQuery.

Guide to Sample Size

An Introduction to Adaptive Clinical Trial Designs | Guest Blog Post

This guest post from Quanticate is a great introduction to adaptive clinical trial designs.

Adaptive Clinical Trials

New FDA Guidance on Adaptive Clinical Trial Design

The FDA published the revised draft guidance on "Adaptive Designs for Clinical Trials of Drugs and Biologics". This is a quick summary of the guidance and what sample size challenges and opportunities are present.

Guide to Sample Size

Optimizing Trial Design [Webinar]

[Video] How to optimize phase I,II and phase III of your clinical trial design

Guide to Sample Size

Simon's Two Stage Design

Simon's Two-Stage Design is a type of phase II clinical trial design. This blog and video examine how to use Simon's Two-Stage in your clinical trial design planning.

Guide to Sample Size

Sample Size for Phase II | Simon’s Two-Stage Design and MCP-Mod

[Video] We cover how to design and find the appropriate sample size for two common Phase II methods: Simon’s Two-Stage Design and MCP-Mod.

Guide to Sample Size

What clinical trial challenges do biostatisticians face?

[Guide} What Clinical Trial Challenges Biostatisticians Face? | Design Constraints - Statistical/Analysis Challenges - Flexible Design. We examine the challenges and steps to overcome them.

Guide to Sample Size

Confidence Interval & Precision Sample Size

Examine Confidence Interval (CI) and the role of precision sample size.

Adaptive Clinical Trials

Unblinded Sample Size Re-Estimation for Survival Analysis

What is unblinded sample size re-estimation and how do we obtain this sample size calculation? Let us quickly examine them and how they can impact your work. For more information on this topic, check out our full webinar - The Advantages and Disadvantages of Sample Size Re-estimation

Guide to Sample Size

What Are The Top Statistics Blogs?

What are some of the top stats blogs or websites I should follow? We list 10 of the best stats blogs to get you started.

News & Events

JSM 2019, Denver - Review from nQuery Sample Size Software

Members of the nQuery Sample Size Software team went to Denver for the 2019 Joint Statistical Meetings (JSM). Read a quick overview of the highlights & insights from JSM 2019.

Guide to Sample Size

Free Sample Size Software vs nQuery

A Free Sample Size Calculator - Why choose nQuery as your statistical sample size calculator when there are freeware options available?

Guide to Sample Size

Why to include Bayesian statistics when planning your frequentist trial (Webinar)

[Webinar] Why to include Bayesian Statistics when planning your frequentists trial | In this free webinar you will learn about why you should integrate Bayesian statistics when planning a trial and how you can start integrating Bayesian methods into your frequentist work

News & Events

Win a $500 Amazon Gift Card at JSM 2019 with nQuery

Add to your JSM 2019 Program - Win a $500 Amazon gift card with nQuery at the 2019 Joint Statistical Meeting | | Enjoy some great food and beverages at the nQuery mixer and reception at JSM 2019. Register and drop by MONDAY JULY 29th | 6-7pm.

Guide to Sample Size

Dealing with Design Constraints via Hierarchical and Mixed Models

nQuery Lead Researcher, Ronan Fitzpatrick uses worked examples to cover dealing with design constraints such as Multi-centre/Hierarchical Effects. This video is an except from our May 2019 webinar, Innovative Strategies For Successful Trial Design.

Guide to Sample Size

What Statistical Considerations to take in Clinical Trial Designs

[Guide} What statistical considerations to take in clinical trial designs? Statistical choices have an important effect on what trial questions/hypotheses are of interest & how to answer them.

Adaptive Clinical Trials

Sample Size For Survival Analysis - A guide to planning successful clinical trials (Webinar)

[Webinar] Sample Size for Survival Analysis - A guide to planning successful clinical trials | In this free webinar, you will learn about the new and established design strategies available to you for planning a survival analysis by using practical examples throughout.

News & Events

nQuery Summer 2019 Release | 41 new sample size tables

41 new sample size tables | From fixed to flexible trial designs, the nQuery Summer 2019 release (ver 8.4) sees the continued strengthening of nQuery to help Biostatisticians and clinical researchers save costs, reduce risk and help clinical trials be successful.

Guide to Sample Size

Innovative Strategies For Successful Trial Design (Webinar)

In this webinar, we examine some design strategies available to you followed by how to apply these in order to calculate the correct sample size for your study. Today drug development faces very different challenges than before. High failure rates, long development time and increasing cost means it must adapt accordingly. This webinar examines these issues.

Guide to Sample Size

Adaptive Design - Your Strategy for Successful Oncology Trials

Adaptive Design - Your Strategy for Successful Oncology Trials. To make clinical trials faster, less costly and more successful, Biopharmaceutical companies are moving from fixed to flexible study designs. See how the new release of nQuery can help your oncology trials.

Guide to Sample Size

Dealing with Uncertainty in Clinical Trials - with Ronan Fitzpatrick & Prof. Stephen Senn

Statsols Head of Statistics & nQuery Lead Researcher, Ronan Fitzpatrick had the chance to sit down with Professor Stephen Senn discuss dealing with Uncertainty in Clinical Trials. This video is an excerpt from a feature length video titled "nQuery Interviews Professor Stephen Senn". The full video interview is available to watch on-demand now.

Bayesian Clinical Trials

Bayesian Sample Size & n-of-1 Trials - with Ronan Fitzpatrick & Prof. Stephen Senn

Statsols Head of Statistics & nQuery Lead Researcher, Ronan Fitzpatrick sat down to chat with Professor Stephen Senn about Bayesian Sample Size and n-of-1 Trials. Bayesian Sample Size & n-of-1 Trials. Read more to learn about Bayesian Sample Size and n-of-1 Trials.

Guide to Sample Size

Effect Size & Sensitivity Analysis - with Ronan Fitzpatrick & Prof. Stephen Senn

Statsols Head of Statistics & nQuery Lead Researcher, Ronan Fitzpatrick recently sat down with Professor Stephen Senn to talk about Effect Size & Sensitivity Analysis. This video is an excerpt from a feature length video titled "nQuery Interviews Professor Stephen Senn". The full video interview is available to watch on-demand now.

Guide to Sample Size

Sample Size in Clinical Trial Design - with Ronan Fitzpatrick & Stephen Senn

Statsols Head of Statistics and nQuery Lead Researcher, Ronan Fitzpatrick had a chance to sit down with Professor Stephen Senn to talk about Sample Size in Clinical Trial Design. The full video interview is available to watch on-demand now.

Adaptive Clinical Trials

How To Calculate Blinded Sample Size Re-Estimation in Clinical Trials

What is unblinded sample size re-estimation? Let us quickly examine how to calculate sample size for unblinded SSR

Adaptive Clinical Trials

How To Calculate Unblinded Sample Size Re-Estimation in Clinical Trials

What is unblinded sample size re-estimation? Let us quickly examine this and how unblinded SSR can impact your work.

Adaptive Clinical Trials

The Advantages & Disadvantages of Unblinded Sample Size Re-Estimation

What are the advantages & disadvantages of unblinded sample size re-estimation in clinical trials? How to calculate the correct sample size for unblinded SSR? Let us quickly examine unblinded SSR and how this trial design may help you.

Adaptive Clinical Trials

What is Unblinded Sample Size Re-Estimation in Clinical Trials?

What is Unblinded Sample Size Re-Estimation in Clinical Trials? How do I perform a sample size calculation or power analysis for unblinded SSR? Read our blog for more details on these questions.

Adaptive Clinical Trials

What is Sample Size Re-Estimation?

What is Sample Size Re-Estimation in Clinical Trials? How to calculate sample size and power analysis in a sample size calculator for SSR? Let us quickly look at what Sample Size Re-Estimation in Clinical Trials means for you as a researcher.

What is the ROI of nQuery?

What is the ROI of nQuery? nQuery is providing true ROI for pharmaceutical companies, CRO organizations and academic institutions. See the reasons why.

Adaptive Clinical Trials

The Advantages & Disadvantages of Blinded Sample Size Re-Estimation

What are the advantages & disadvantages of blinded sample size re-estimation in clinical trials? Let us quickly examine them and how they can impact your study. For more information on this topic, check out our full webinar - The Advantages and Disadvantages of Sample Size Re-estimation

Adaptive Clinical Trials

What Are Adaptive Clinical Trials? (and why use them)

What are adaptive design clinical trials? How to conduct sample size calculation for adaptive trials? Let us quickly look at the advantages of adaptive designs in clinical trials and what they mean for you. For more information on this topic, check out our full webinar - The Advantages and Disadvantages of Sample Size Re-estimation.

Adaptive Clinical Trials

[Guide] What To Look For In A Sample Size Calculator

[Guide] What to look for in a sample size calculator. Using a sample size calculator to determine the appropriate sample size is a crucial step in study design. So what do you look for in a sample size calculator? This guide lists the most important factors you need to know when deciding what software to use for this important part of your study.

Adaptive Clinical Trials

5 Reasons Biostatisticians are using nQuery for Adaptive Clinical Trials

Discover the top 5 reasons why Biostatisticians are choosing nQuery for Adaptive Clinical Trials.

Guide to Sample Size

Clinical Trial Design & Sample Size Calculation Mistakes To Avoid

The calculation of the correct sample size is one of the first and most important steps in clinical trials. Read the list of sample size determination practices to be avoided as per the E9 Statistical Principles for Clinical Trials found in the FDA Guidance for industry.

Guide to Sample Size

15 Ways to Reduce Sample Size In Clinical Trials

How to reduce sample size in clinical trials? Retain statistical significance and the correct power in your clinical trial design - but reduce the cost.

Guide to Sample Size

New FDA Guidance on Seamless Clinical Trials

The FDA recently published a draft guidance that it believes will help accelerate drug development without compromising patient safety in the area of oncology. This is a quick summary of this guidance and what sample size challenges and opportunities are present.

News & Events

Highlights from JSM 2018 | Vancouver

Members of the nQuery Sample Size Software team went to Vancouver for the 2018 Joint Statistical Meetings (JSM). Read a quick overview of the highlights & insights from JSM including the Bayesian technology workshop that our Head of Statistics - Ronan Fitzpatrick - hosted at JSM 2018.

Bayesian Clinical Trials

5 Reasons Why Researchers Are Using nQuery To Calculate Bayesian Assurance

Bayesian Assurance has risen in popularity. See 5 reasons why researchers are using nQuery to calculate Bayesian Assurance.

News & Events

Say hello to the nQuery Sample Size Software Team at JSM 2018

If you are going to JSM this year, drop by the nQuery Sample Size Software booth (#328) to meet some members of our team, talk all things sample size and give us your thoughts on nQuery! We would love to see you there. #LeadwithStatistics

Guide to Sample Size

The 5 Essential Steps for Sample Size Determination (Webinar)

Rewatch our webinar that was hosted by nQuery Researcher & Statistician Eimear Keyes, where we map out the 5 essential steps for sample size determination in clinical trials. At each step, Eimear highlights the important function it plays and how to avoid the errors that will negatively impact your sample size determination and therefore your study.

Guide to Sample Size

Overcoming Sample Size Challenges: Practical Methods for Study Success

Join our webinar with Ronan Fitzpatrick, to tackle calculation, overcome sample size challenges and study design issues effectively.

Bayesian Clinical Trials

A Brief Overview of Bayesian Analysis for Biostatisticians

Bayesian methods are becoming more common in clinical trials. Previously, a lack of computing power in sample size software hindered the use of these methods, but improvements in the area have led to more widespread use. To examine what’s new and different about Bayesian sample size determination, we first need to consider what’s done in a traditional setting.

Bayesian Clinical Trials

5 Reasons Why Pharma Companies Are Calculating Bayesian Assurance

The pharmaceutical industry is increasingly turning to Bayesian methods in an attempt to improve efficiency and enhance decision making. Assurance (Bayesian Power) is becoming a key feature of these Bayesian methods. This is not to replace traditional power but to complement it.

Guide to Sample Size

Maximum-Tolerated Dose & the Continual Reassessment Method

Quickly determine the Maximum-Tolerated Dose (MTD) through the Continual Reassessment Method. Traditional 3+3 designs can be slow to reach the target dose.

Bayesian Clinical Trials

Why Frequentists are using Bayesian Statistics in Clinical Trial Design

Bayesian statistical methods have become increasingly popular in statistical practice both inside and outside regulated environments. We explore why.

News & Events

Top 10 Corporate Clinical Trial Sponsors of 2016

Following on from our previous blog post, The Most Popular Clinical Trial Drugs of 2016, we thought it would be a good idea to take a closer look at the Top 10 Corporate Clinical Trial Sponsors of 2016

Guide to Sample Size

Wider Integration of Cost Considerations in Sample Size

In this 3 part series Head of Statistics at Statsols, Ronan Fitzpatrick, examines key trends in sample size determination which are being felt in trial design.

Guide to Sample Size

The Effect of Adaptive Trials and Sample Size Re-estimation

In this 3 part series Head of Statistics at Statsols, Ronan Fitzpatrick, examines key trends in sample size determination which are being felt in trial design.

Guide to Sample Size

Integrating Uncertainty in Parameter Estimates

In this 3 part series Head of Statistics at Statsols, Ronan Fitzpatrick, examines key trends in sample size determination which are being felt in trial design.

Most Popular Clinical Trial Drugs of 2016

Currently, there are over 205,000 registered clinical trials underway throughout the globe. In 2016 over 14,000 new trials were initiated and we thought it would be useful to look at the top drugs under investigation for the year just past. We further analysed the trials by phase and by sponsor type to get a clearer picture of the 2016 clinical trial landscape.

Why do phase III clinical trials fail?

Why do phase III clinical trials fail and how can we improve them? Dr. Grignolo, PhD, Corporate Vice President of PAREXEL International, the multinational life sciences consulting firm, recently examined this issue in a paper tilted: Phase III Trial Failures: Costly, But Preventable.

Guide to Sample Size

What is the difference between Superiority vs. Equivalence vs. Non-inferiority in clinical trial design

Your sample size or power calculation for clinical trials depends on your trial design. Learn about Superiority vs. Equivalence vs. Non-inferiority in clinical trial design.

Making it personal: N-of-1 trials, allowing for individuality but not overdoing it

Guest Blog: Recognised as a leading global authority on clinical biostatistics. Stephen Senn is a former member of the Statsols statistical advisory board and he currently serves as a consultant to our statistical development team. In this guest blog Stephen gives his thoughts on n-of-1 trials

Intact social cognitive processes in outpatients with anorexia nervosa: a pilot study

Social cognition Emotion recognition Facial perception EmpathyTheory of mind

STUDY: Pre-surgical depression and anxiety and recovery following coronary artery bypass graft surgery

Depression AnxietyCoronary artery bypass graft surgery RecoveryMajor adverse cardiac events Pain Longitudinal study

Clinical Trials Data Dive - Results from 220,000 clinical trials

Infographic: We looked at trends from 220,000+ Clinical Trials to find 2015/2016 trends including what sample size calculator was used

Power Combined with Precision Helps Improve Sample Size Justification

On foot of the ASA P values statement, Ronan Fitzpatrick looks at how power analysis and sample size justification improved clinical research quality.

Thoughts on the ASA P Values Statement

Ronan Fitzpatrick, Statistician considers the issues surrounding the ASA's p-values statement.

Monday at JSM 2015, what are you attending?

JSM 2015 - Talks on missing data, multiple imputation, hot decking. Applications in government statistics and survey response.

An Overview of Multiple Imputation in SOLAS for Missing Data 5.0

Multiple imputation methods in Solas 5. Hot deck imputation, predictive modelling, propensity scoring matching, mahalanobis distance matching and more

Missing Data - A Pervasive Problem in Data Analysis

Missing Data Analysis significantly reduces reliability in any dataset. What impact does missing data have?

Why is Sample Size Important?

Learn about the importance of calculating sample size for clinical trials. See: How to Calculate Sample Size in 4 Easy Steps.

Data Integration and Visualization

Today’s complex clinical trials yield data sets that are almost unimaginably large and complex.

New lung cancer detection instrument moving to clinical trials stage

Owlstone Nanotech, the developers of a promising new lung cancer detection instrument have announced they are now moving their device into clinical trials.

Institute of Medicine releases report “Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk”

The Institute of Medicine has released a report called “Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk”

nQuery Advisor + nTerim used to calculate sample size at St James Hospital, Dublin.

nQuery Advisor + nTerim used to calculate sample size in study recently published in January edition of EJOP

Clinical trials to begin soon for eZMapp, created by Mapp Biopharmaceutical.

The experimental ZMapp treatment created by Mapp Biopharmaceutical will soon begin human clinical trials in the United States and Liberia, following efforts to boost production capacity.

Clinical trial combo started by Amgen and Merck

Amgen & Merck launch early-stage clinical trial pairing their respective cancer immunotherapies, to confirm promise of a combo approach to cancer.

Brincidofovir a very-broad-spectrum antiviral drug?

Brincidofovir is an oral antiviral drug being tested to fight more common viruses, including one that infects patients undergoing bone marrow transplants. Laboratory tests suggested it might also fight Ebola.

Johnson and Johnson to Start Ebola Vaccine Trial in 2015

Johnson & Johnson will speed development of a new combination Ebola vaccine, with a clinical trial planned for early 2015.

What is a Meta Analysis

Meta analysis is the statistical procedure for combining data from multiple studies for the purposes of research.

GSK to start Clinical Trial on Ebola Vaccine

Glaxo Smith Kline will soon start a clinical trial of an experimental ebola vaccine against the deadly Ebola virus, which it is co-developing with U.S scientists.

Happy Birthday Statistical Solutions

Happy Birthday Statistical Solutions

nQuery Advisor + nTerim now sold on subscription.

nQuery Advisor + nTerim is now available to new and existing customers on subscription, lower yearly fee and no more high acquisition costs.

Happy 4th July!

Happy 4th July!

Clinical trial data to be made available for download.

EMA policy change: Clinical trial data submitted in the EU must be made available for downloading for academic and non-commercial research purposes.

Homeward bound from DIA

Homeward bound from DIA 2014 50th Annual Meeting. See you all again next year.

Sample Size

The two major factors affecting the power of a study are the sample size and the effect size. The larger the sample size is the smaller the effect size.

Infographic: The process of discovering and bringing a new drug to the public

Great Info-graphic showing the cost and process of discovering and bringing a new drug to the market

FDA recommends bioequivalence standards for 26 drugs

New guidance from the FDA for bioequivalence studies for 26 new products, Nexium, Cymbalta, Celebrex, Actonel, Gleevec, Avodart, Crestor, Benicar and more.

The DIA 2014 50th Annual Meeting

Statsols will attend DIA 2014 50th Annual Meeting. Many sessions on Multiregional Clinical Trials, Design and Sample Size, Missing Data in Clinical Trials.

New Release - nQuery Advisor + nTerim 3.0

nQuery Advisor + nTerim is now available for purchase and upgrades. nQuery Advisor + nTerim 3.0 features great new sample size tables for Regression and Means, some of which are completely unique to this latest version

Introducing the nQuery Advisor + nTerim Campus Licence.

Introducing the nQuery Advisor + nTerim Campus Licence.

nQuery Advisor User Group for Clinical Trials.

User group for clinical trials for exiting & future users of nQuery Advisor to support, share and draw from one anothers experiences.

A Celebration of Don Rubin on His 70th Birthday

The Department of Statistics, Harvard University, Cambridge, MA will hold a celebration honouring Don Rubin on his 70th Birthday on Sat March 29, 2014.

The World of Statistics launch new website

Learn more about The World of Statistics, visit th its new website www.worldofstatistics.org

New Year, New Website

New Year, New Website

The Prevention and Treatment of Missing Data in Clinical Trials

The Prevention and Treatment of Missing Data in Clinical Trials

Free Webinar…..Multiple Imputation in Pharmaceutical Clinical Trials

Free Webinar…..Multiple Imputation in Pharmaceutical Clinical Trials

ISI Dublin + JSM Miami Reports

ISI Dublin + JSM Miami Reports

Report on 4th Workshop on Analysis of Incomplete Data (AID), Bamberg, Germany

Report on 4th Workshop on Analysis of Incomplete Data (AID), Bamberg, Germany

PSI Expert Group on Missing Data

PSI Expert Group on Missing Data

Power and Sample Size for Group Sequential Trials

Power and Sample Size Software for Group Sequential Trials

BMDP Statistical Software in Cutting Edge Research

Researchers at various North American universities use BDMP statistical software for their innovative research projects to analyze very large data sets.