15 Ways To Reduce Sample Size in Clinical Trials

 

How to reduce sample size without losing power in clinical trials?

Reducing sample size without losing power can be accomplished in one of three principles.

  • Improve the signal-to-noise ratio. To do this, you can either reduce the noise, strengthen the signal, or reduce variability (which will both reduce the noise and strengthen the signal). 
  • Use a better statistical technique. By doing this you may be able to extract more information out of your data.
  • Multiplex. On a basic level this involves using the the same patient more than once.

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