read the detailed version

**Reducing sample size without losing power can be accomplished in one of three principles.**

**Improve the signal-to-noise ratio.**To do this, you can either reduce the noise, strengthen the signal, or reduce variability (which will both reduce the noise and strengthen the signal).

**Use a better statistical technique.**By doing this you may be able to extract more information out of your data.

**Multiplex.**On a basic level this involves using the the same patient more than once.

**Complete the form to read the detailed version of the****15 ways to reduce sample size in clinical trials.**

**To view the complete paper with explanations, quickly complete the form.**