nQuery vs East — Head-to-Head Comparison | nQuery

Competitive Comparison

nQuery versus East

Same capabilities. Simpler licensing. Significantly lower cost.

Head-to-Head Comparison

nQuery covers every core East capability — at a fraction of the cost

Capability nQuery East
Fixed Term Power + Sample Size
Survival Analysis Sample Size
Group Sequential Design
Unblinded SSR (Promising Zone)
Multiple Comparison Procedures
Multi-Arm Multi-Stage (MAMS)
Simon's Two-Stage Design
Multiple Comparison-Modelling (MCPMod)
Assurance (Bayesian Power)
Milestone Prediction Simulation
2×2 Crossover Designs

Where nQuery goes further

Internal Pilot Design

Blinded Sample Size Re-estimation

Re-estimate sample size for continuous, binary and count data while preserving trial integrity and accounting for pre-trial misspecification.

Non-proportional hazards and more

Advanced Survival Analysis

Find the right method for your oncology trial: Linear-Rank Tests, MaxCombo, RMST, AFT + One-arm, Paired, Stratified and Competing Risks Log-Rank Tests.

Bayesian Power and Intervals

Bayesian Sample Size

Integrate priors into your study planning. Sample Size for Credible Interval Precision and Power for Bayesian testing using Bayes Factors or Posterior Errors.

Additional models and designs

Counts and Recurrent Events

Comprehensive design solutions for Poisson and Negative Binomial models + Group Sequential, Crossover, Andersen-Gill, Non-inferiority and Equivalence options.

Trial Feasibility & Parameter Precision

Pilot Study Size

Find the right size for your pilot study to ensure a sufficiently precise estimate for your variance estimate or to conduct problem detection for trial feasibility.

Higher-order and Adaptive BE Designs

Complex Bioequivalence

Beyond 2×2: Power and sample size for eight higher-order crossover designs + two-stage adaptive (Potvin, Maurer) and Bayesian (ROPE, Bayes Factor) designs.

Four simple tiers with free yearly updates.
No confusing modules.

Base
Fixed Term Sample Size

Power and sample size for continuous, discrete, survival, count + more

  • Planning for 1000s of Fixed Term Trial Scenarios
  • Wide variety of popular endpoints and designs
  • Plus Regression, Correlation and Agreement
  • Confidence, Prediction and Tolerance Intervals
Plus
Bayesian + Fixed Term

Bayesian Power calculations and sample size for Bayesian Intervals and Tests

  • Assurance using Conjugate, Uniform or Custom Priors
  • Credible and Bayesian/Frequentist Intervals
  • Testing using Posterior Error Rates
  • Bayes Factors for Superiority and Equivalence Testing
Most Popular
Pro
Adaptive + Bayesian + Fixed

Plan and explore complex adaptive designs in line with regulatory guidance

  • Group Sequential Design with wide range of boundary methods
  • Unblinded and Blinded Sample Size Re-estimation
  • Multi-Arm Multi-Stage Designs (MAMS)
  • Phase II Designs (Simon's Two-Stage, MCP-Mod)
Expert
Prediction + All Lower Tiers

Predict interim or final analysis timings based on accrual or event milestones

  • Prediction for Accrual and Events Milestones
  • Global or Site-Level Accrual Rate Inputs
  • Constant or Piecewise Poisson Accrual Models
  • Exponential and Weibull Models for Events and Dropout