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Unblinded Sample Size Re-estimation Template

What is unblinded sample size re-estimation?

An unblinded sample size re-estimation is done by increasing the sample size in response to an interim effect size that is ‘promising’. The uncertainty that you’re taking from the initial sample size determination will be around the effect size.

Recommended Viewing:
24.58s
Group Sequential Design30:10s - Unblinded Sample Size Re-estimation | 31:26s Two Sample Mean Blinded SSR
|
41:54s Two Sample Binomial SSR

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