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In Group Sequential Design, data is analyzed at multiple points during the course of the trial, rather than waiting until the end of the trial to analyze data.
Recommended Viewing:
28.01s - Group Sequential Design
30:10s - Unblinded Sample Size Re-estimation
31:26s - Two Sample Mean Blinded SSR
41:54s - Two Sample Binomial SSR
Download Unblinded Sample Size Re-estimation Template sample data
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Download Blinded sample size re-estimation - Two sample mean sample data
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Download Blinded sample size re-estimation - Two sample binomial sample data
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