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CLASSICAL

Solutions for Frequentist and Fixed-term trials
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BAYESIAN

Sample size using Bayesian analysis
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ADAPTIVE

Sample size for sophisticated Adaptive clinical trials

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Sample Size Determination

Hypothesis Testing Examples

Sample size examples by statistical & therapeutic areas
(for video tutorials, view our past webinars here)

Leukemia/Oncology

Sample Size Example

Tags: Simon's Two-Stage Design, Proportions, Oncology, Adaptive

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Gynecologic Oncology

Sample Size Example

Tags: Simon's Two-Stage Design, Proportions, Oncology, Adaptive

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Cardiac Surgery Survival

Sample Size Example

Tags: Proportions, Unblinded SSR, Cardiology, Adaptive

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Rare Immune System Disorder

Sample Size Example

Tags: Andersen-Gill, Recurrent Events, Immunology

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COPD Research

Sample Size Example

Tags: Two Negative Binomial, Means, Respiratory

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Anti-depressant Therapy

Sample Size Example

Tags: MCP-MOD, Means, Neurology, Adaptive

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Coronary Heart Disease

Sample Size Example

Tags: Agreement, Cardiology

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Thrombosis

Sample Size Example

Tags: Agreement, Cardiology

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Hepatology

Sample Size Example

Tags: Agreement, Oncology

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Prostate Cancer Study

Sample Size Example

Tags: Agreement, Urology

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Dairy Science

Sample Size Example

Tags: Agreement, Veterinary

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Diabetes

Sample Size Example

Tags: Means, Cardiology

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Pulmonary Hypertension

Sample Size Example

Tags: Means, Cardiology

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Immunology CRT

Sample Size Example

Tags: Means, Immunology

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Nephrology

Sample Size Example

Tags: Means, Nephrology

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Multiple Sclerosis

Sample Size Example

Tags: Means, Neurology

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Lung Disease

Sample Size Example

Tags: Means, Respiratory

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Respiratory

Sample Size Example

Tags: Means, Respiratory

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COPD

Sample Size Example

Tags: Means, Respiratory

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Allergic Rhinitis

Sample Size Example

Tags: Means, Respiratory

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Urinary Incontinence

Sample Size Example

Tags: Means, Urology, Adaptive

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Neurogenic Detrusor

Sample Size Example

Tags: Means, Urology

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Psoriatic Arthritis

Sample Size Example

Tags: Proportions, Rheumatology

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Veterinary

Sample Size Example

Tags: Proportions, Veterinary

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Multiple Sclerosis

Sample Size Example

Tags: Regression, Neurology

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Atrial Fibrillation

Sample Size Example

Tags: Survival Analysis, Cardiology

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Metastatic Colorectal Cancer

Sample Size Example

Tags: Survival Analysis, Oncology, Adaptive

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Liver Disease

Sample Size Example

Tags: Survival Analysis, Oncology, Adaptive

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Prefer videos?
Webinar recordings are available here.


Sample Size Examples

Here you can sort the hypothesis testing examples by statistical or therapeutic area to suit your sample size needs. These examples cover sample size or power analysis for 3 different types of clinical trials - Classical, Bayesian and Adaptive clinical trial design.  nQuery covers over 1000+ sample size & statistical procedures and offers innovative techniques such as Bayesian & Adaptive trial design to reduce the risk and costs associated with clinical trials.

What is a hypothesis? A hypothesis is a supposition or proposed explanation made on the basis of limited evidence as a starting point for further investigation. Here you will find hypothesis testing examples using nQuery. These are real world industry examples that are recreated in nQuery to demonstrate how nQuery can be used for calculating sample size. They cover a range of different statistical and therapeutic areas. nQuery covers over 1000+ sample size & statistical procedures to help you with your clinical trial design.

nQuery in Scientific Journals

nQuery is extensively featured in Scientific Journals. Over 1000 citations are listed with The NCBI alone.

A list of nQuery scientific citations is available here.